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News
July 3rd, 2017
Paving the way toward tooth regeneration
Enamel, formed by ameloblast cells, is the hardest substance in human body, and the first defensive line for healthy tooth. Unfortunately, nearly 40% the incisor teeth in babies and children have some sort of enamel defect. To replace enamel, or even entire teeth, [...]
July 3rd, 2017
COR researchers found that fluoride targets Androgen Receptor (AR) and Progesterone Receptor (PR) driven Klk4 transcription in maturation ameloblasts
Kallikrein related peptidase 4 (KLK4) is thought to play important role in the final stage of dental enamel formation by allowing for enamel crystal growth. In humans having a mutated KLK4 gene and in mice lacking Klk4 expression, the enamel becomes hypomineralized [...]
May 16th, 2016
Dr Ann George visited COR from University of Illinois, Chicago
Dr Ann George visited COR on April, 2016 from the University of Illinois and gave the lecture on the topic "DMP1: A busy protein that functions in mineralized matrix assembly". Dr George is a Professor at the Division of Oral Biology, University of [...]
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